GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
THYM | cis | rs1577917 | 1 | rs13196930 | chr6:86652245 | SNHG5 | chr6:86386726-86388451:- | -0.6 | -7.24 | 1.15E-10 | Response to antipsychotic treatment |
THYM | cis | rs1577917 | 1 | rs13199006 | chr6:86608708 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -7.62 | 1.9E-11 | Response to antipsychotic treatment |
THYM | cis | rs1577917 | 1 | rs13217384 | chr6:86720000 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
THYM | cis | rs2243480 | 1 | rs13220979 | chr7:65363204 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 4.78 | 6.3E-6 | Diabetic kidney disease |
THYM | cis | rs2243480 | 1 | rs13235972 | chr7:65883605 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
THYM | cis | rs2243480 | 1 | rs13237037 | chr7:65997882 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
THYM | cis | rs2243480 | 1 | rs13247184 | chr7:65358928 | CCT6P1 | chr7:65216092-65228661:+ | 0.68 | 5.01 | 2.55E-6 | Diabetic kidney disease |
THYM | cis | rs1325195 | 1 | rs1325195 | chr1:179071756 | ABL2 | chr1:179068463-179198819:- | -0.32 | -4.23 | 5.44E-5 | IgE grass sensitization |
THYM | cis | rs7017914 | 1 | rs13252719 | chr8:71734569 | XKR9 | chr8:71581600-71648176:+ | 0.84 | 10.7 | 5.33E-18 | Bone mineral density |
THYM | cis | rs7017914 | 1 | rs13253842 | chr8:71625503 | XKR9 | chr8:71581600-71648176:+ | 0.84 | 10.55 | 1.11E-17 | Bone mineral density |
THYM | cis | rs1364705 | 1 | rs13262685 | chr8:120226145 | MAL2 | chr8:120220610-120257911:+ | 0.42 | 4.42 | 2.6E-5 | Hippocampal atrophy |
THYM | cis | rs2243480 | 1 | rs13310597 | chr7:65598540 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.31 | 7.1E-7 | Diabetic kidney disease |
THYM | cis | rs9876781 | 1 | rs13314659 | chr3:48449149 | TREX1 | chr3:48501186-48509043:+ | 0.29 | 4.43 | 2.49E-5 | Longevity |
THYM | cis | rs10935120 | 1 | rs13322305 | chr3:134310791 | ANAPC13 | chr3:134196547-134204865:- | 0.55 | 7.48 | 3.7E-11 | Height |
THYM | cis | rs10935120 | 1 | rs13322305 | chr3:134310791 | CEP63 | chr3:134204575-134293852:+ | 0.43 | 6.36 | 7.09E-9 | Height |